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Perfusion-targeted approaches have shown superior outcomes inpatients with intact autoregulation, while the contrary has been true in those with impairedautoregulation, where intracranial pressure (ICP)-directed management has conferred bet-ter outcomes (9). Signs of inflammatorychanges (bleeding upon probing, suppuration, color changes associated withinflammation, etc.) should be noted and recorded. Vitamin D and cardio-vascular disease will it live up to its hype? J Am CollCardiol. Increasesin mCHC are associated with spherocytosis, intravascularhemolysis, and cold agglutins.
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